Motif ID: DMAP1_NCOR{1,2}_SMARC.p2

Z-value: 2.555


Transcription factors associated with DMAP1_NCOR{1,2}_SMARC.p2:

Gene SymbolEntrez IDGene Name
DMAP1 55929 DNA methyltransferase 1 associated protein 1
NCOR1 9611 nuclear receptor co-repressor 1
NCOR2 9612 nuclear receptor co-repressor 2
SMARCA1 6594 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA5 8467 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC2 6601 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SMARCC2chr12_-_548695680.533.4e-02Click!
NCOR2chr12_-_1236179620.421.1e-01Click!
SMARCA1chrX_-_128485062-0.381.5e-01Click!
DMAP1chr1_+_444516980.332.1e-01Click!
NCOR1chr17_-_160386070.282.9e-01Click!
SMARCA5chr4_+_144654005-0.184.9e-01Click!


Activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2.

activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2


Sorted Z-values histogram for motif DMAP1_NCOR{1,2}_SMARC.p2

Sorted Z-values for motif DMAP1_NCOR{1,2}_SMARC.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DMAP1_NCOR{1,2}_SMARC.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_120799411 8.965 NM_015900
PLA1A
phospholipase A1 member A
chr15_+_42815851 8.836 NM_080745
NM_182985
TRIM69

tripartite motif containing 69

chr10_-_11614279 6.805 NM_001080491
USP6NL
USP6 N-terminal like
chrX_+_78087484 6.667 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr5_-_138753443 6.400 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chrX_-_30505804 6.133 NM_025159
CXorf21
chromosome X open reading frame 21
chr16_+_48865521 5.810 ADCY7
adenylate cyclase 7
chr13_+_23042722 5.499 NM_148957
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr7_+_73826244 5.335 NM_000265
NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chr3_+_123279439 5.321 NM_006889
CD86
CD86 molecule
chr17_+_22823151 5.065 NM_014238
KSR1
kinase suppressor of ras 1
chr16_+_10878539 4.976 NM_000246
CIITA
class II, major histocompatibility complex, transactivator
chr2_+_143603439 4.842 ARHGAP15
Rho GTPase activating protein 15
chr14_+_99601498 4.838 NM_016337
EVL
Enah/Vasp-like
chr2_+_143603368 4.799 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr14_+_99601517 4.780 EVL
Enah/Vasp-like
chr1_+_165564904 4.719 NM_001198783
POU2F1
POU class 2 homeobox 1
chr19_-_10074332 4.508 NM_031917
ANGPTL6
angiopoietin-like 6
chr14_+_75058518 4.492 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chr12_-_15005761 4.367 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr6_-_33016561 4.346 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr1_-_205161821 4.339 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr17_-_78000890 4.305 NM_001193655
C17orf62
chromosome 17 open reading frame 62
chr14_+_75058591 4.299 BATF
basic leucine zipper transcription factor, ATF-like
chr1_+_165565006 4.090 POU2F1
POU class 2 homeobox 1
chr11_+_5602782 3.922 NM_021616
TRIM34
tripartite motif containing 34
chr6_+_52159143 3.669 NM_002190
IL17A
interleukin 17A
chr17_+_6600080 3.577 XAF1
XIAP associated factor 1
chr1_+_32489426 3.408 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr3_-_113495763 3.359 NM_183061
SLC9A10
solute carrier family 9, member 10
chr3_+_188568861 3.304 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr5_-_142795269 3.265 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr5_-_149772528 3.224


chr1_-_149586298 3.174 RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr20_+_44180296 3.123 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr5_-_149772469 3.123 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr20_+_44180355 3.117 CD40
CD40 molecule, TNF receptor superfamily member 5
chr7_+_128795178 3.115 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr1_-_149586341 3.110 NM_000449
NM_001025603
RFX5

regulatory factor X, 5 (influences HLA class II expression)

chr9_+_126460511 2.998


chr6_+_31647854 2.992 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr6_+_70633168 2.984 NM_001858
COL19A1
collagen, type XIX, alpha 1
chr11_+_303852 2.958 NM_003641
IFITM1
interferon induced transmembrane protein 1 (9-27)
chr7_+_73145481 2.864 LIMK1
LIM domain kinase 1
chr7_+_128795280 2.845 AHCYL2
adenosylhomocysteinase-like 2
chr19_+_17723285 2.835 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr5_-_169657312 2.809 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr19_+_17377502 2.734 LOC100507535
hypothetical LOC100507535
chr18_+_13601664 2.723 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr19_-_40925151 2.698 NM_024660
TMEM149
transmembrane protein 149
chr17_-_31231421 2.696 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr12_-_119961143 2.695 NM_003733
NM_198213
OASL

2'-5'-oligoadenylate synthetase-like

chr17_+_44643067 2.681 ABI3
ABI family, member 3
chr19_-_2036227 2.635 MOBKL2A
MOB1, Mps One Binder kinase activator-like 2A (yeast)
chr12_+_25096472 2.600 NM_006152
LRMP
lymphoid-restricted membrane protein
chr12_-_9777126 2.593 NM_172004
CLECL1
C-type lectin-like 1
chr4_+_39874921 2.543 NM_004310
RHOH
ras homolog gene family, member H
chr2_-_213723298 2.518 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr10_+_91082218 2.507 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr15_+_86983038 2.478 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr17_-_44642934 2.448 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr5_-_169657192 2.440 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr17_-_26665213 2.431 EVI2B
ecotropic viral integration site 2B
chr1_-_181889070 2.423 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr5_-_169657395 2.413 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr11_+_71387572 2.411 NM_001039659
NM_001039660
NM_173042
IL18BP


interleukin 18 binding protein


chr17_-_37518213 2.382 NM_024119
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr19_-_44518465 2.377 GMFG
glia maturation factor, gamma
chr22_+_38627031 2.367 NM_004810
GRAP2
GRB2-related adaptor protein 2
chr19_-_44518516 2.317 NM_004877
GMFG
glia maturation factor, gamma
chr2_-_215711313 2.313 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr1_-_159306327 2.281 ARHGAP30
Rho GTPase activating protein 30
chr3_+_190831909 2.235 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr5_-_169657360 2.216 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr6_+_29799182 2.213 HLA-F
major histocompatibility complex, class I, F
chr5_-_149772563 2.194 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr22_-_25205376 2.119 NM_152841
HPS4
Hermansky-Pudlak syndrome 4
chr1_-_149004916 2.092 NM_004079
CTSS
cathepsin S
chr16_+_11966464 2.092 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr12_-_47604930 2.088 NM_001143781
FKBP11
FK506 binding protein 11, 19 kDa
chr1_+_100957883 2.058 NM_001078
NM_080682
VCAM1

vascular cell adhesion molecule 1

chr7_+_28418668 2.053 NM_182898
CREB5
cAMP responsive element binding protein 5
chr19_-_55104875 2.017 NUP62
nucleoporin 62kDa
chr17_-_31441390 1.994 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr11_-_104411065 1.993 NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CASP1




caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr1_+_78888064 1.984 NM_006417
IFI44
interferon-induced protein 44
chr1_+_196874839 1.972 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_-_159306369 1.967 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr13_-_102517196 1.937 NM_000452
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chr7_-_76667045 1.902 NM_006682
FGL2
fibrinogen-like 2
chr4_-_38482805 1.900 NM_003263
TLR1
toll-like receptor 1
chr1_-_153098811 1.882 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr3_-_49826221 1.881 UBA7
ubiquitin-like modifier activating enzyme 7
chr16_+_55580910 1.872 NM_032206
NLRC5
NLR family, CARD domain containing 5
chr17_+_6599879 1.868 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr11_+_5667494 1.850 NM_006074
TRIM22
tripartite motif containing 22
chr1_+_40635058 1.834 NM_001198980
SMAP2
small ArfGAP2
chr16_-_88358946 1.821 FANCA
Fanconi anemia, complementation group A
chr12_+_11694172 1.775 ETV6
ets variant 6
chr1_+_159943385 1.757 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr13_-_45654327 1.736 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr22_+_38627129 1.720 GRAP2
GRB2-related adaptor protein 2
chr11_+_71388310 1.703 NM_001145057
IL18BP
interleukin 18 binding protein
chr3_-_58175437 1.678 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr4_+_113958652 1.610 NM_001127493
ANK2
ankyrin 2, neuronal
chr12_-_47605478 1.603 NM_001143782
NM_016594
FKBP11

FK506 binding protein 11, 19 kDa

chr4_+_113437947 1.597 NM_001102406
NM_025144
ALPK1

alpha-kinase 1

chr1_-_9052253 1.575 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr10_+_35466715 1.554 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr6_-_138231006 1.547


chr2_-_37752731 1.522 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr17_+_55854636 1.514 NM_181707
C17orf64
chromosome 17 open reading frame 64
chr6_-_149847718 1.510 ZC3H12D
zinc finger CCCH-type containing 12D
chr17_+_7402788 1.501 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr4_-_153820535 1.493 NM_152680
TMEM154
transmembrane protein 154
chr12_+_6431437 1.487 NM_018009
TAPBPL
TAP binding protein-like
chr12_+_14409875 1.476 NM_018179
ATF7IP
activating transcription factor 7 interacting protein
chr12_+_91620749 1.473 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr1_-_149004879 1.470 CTSS
cathepsin S
chr14_+_23700261 1.470 NM_006084
IRF9
interferon regulatory factor 9
chr13_+_23742846 1.469 SPATA13
spermatogenesis associated 13
chr1_-_9052170 1.455 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr1_+_239762179 1.447 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chrX_+_37524190 1.440 NM_000397
CYBB
cytochrome b-245, beta polypeptide
chr19_+_40895669 1.432 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr19_-_17377383 1.425 NM_004335
BST2
bone marrow stromal cell antigen 2
chr6_-_76259976 1.395 NM_015687
FILIP1
filamin A interacting protein 1
chr1_+_196874759 1.395 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr3_-_114176401 1.383 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr8_-_145132582 1.381 NM_032789
PARP10
poly (ADP-ribose) polymerase family, member 10
chr7_+_150013716 1.381 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr8_-_145132551 1.376 PARP10
poly (ADP-ribose) polymerase family, member 10
chr3_+_186563529 1.351 NM_004721
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr17_-_26665144 1.349 EVI2B
ecotropic viral integration site 2B
chr1_+_938709 1.349 NM_005101
ISG15
ISG15 ubiquitin-like modifier
chr9_+_127550298 1.343 NM_001134778
PBX3
pre-B-cell leukemia homeobox 3
chr6_-_149847809 1.342 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr19_+_16691786 1.321 NM_001007525
NWD1
NACHT and WD repeat domain containing 1
chr4_-_169476391 1.314 NM_017631
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr5_-_88155360 1.301 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr7_-_33047042 1.297 NM_001166118
NM_016489
NT5C3

5'-nucleotidase, cytosolic III

chr1_-_149004852 1.297 CTSS
cathepsin S
chr16_-_28425632 1.284 NM_145659
IL27
interleukin 27
chr5_-_94442941 1.279 MCTP1
multiple C2 domains, transmembrane 1
chr1_-_246869181 1.274 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chrX_+_37524250 1.271 CYBB
cytochrome b-245, beta polypeptide
chr10_-_7491204 1.253 NM_001018039
SFMBT2
Scm-like with four mbt domains 2
chr7_+_119700924 1.231 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr3_-_3127057 1.231 NM_000564
NM_175724
NM_175725
NM_175726
NM_175727
NM_175728
IL5RA





interleukin 5 receptor, alpha





chr15_-_42790805 1.210


chr2_+_61986287 1.207 NM_152516
COMMD1
copper metabolism (Murr1) domain containing 1
chr10_-_1769669 1.202 NM_018702
ADARB2
adenosine deaminase, RNA-specific, B2
chr1_+_154386358 1.201 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_+_32438788 1.194 NM_024296
CCDC28B
coiled-coil domain containing 28B
chr17_-_26665194 1.188 EVI2B
ecotropic viral integration site 2B
chr16_+_27346079 1.185 NM_021798
IL21R
interleukin 21 receptor
chr1_+_32512298 1.152 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr16_-_49272741 1.139 NM_001144972
NM_153337
NM_182854
SNX20


sorting nexin 20


chr1_+_157441824 1.131 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr11_+_63060848 1.129 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr4_-_40211324 1.126 RBM47
RNA binding motif protein 47
chr20_-_51633042 1.120 NM_006526
ZNF217
zinc finger protein 217
chr4_+_38740246 1.119 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr11_-_63808740 1.107 NM_004322
NM_032989
BAD

BCL2-associated agonist of cell death

chr22_-_16080265 1.106 CECR1
cat eye syndrome chromosome region, candidate 1
chr2_+_182030510 1.106 ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr17_-_39094787 1.099 NM_001040002
MEOX1
mesenchyme homeobox 1
chr1_+_84539876 1.086 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr11_+_71388619 1.080 NM_001145055
IL18BP
interleukin 18 binding protein
chr8_+_26206648 1.080 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr3_-_42789738 1.078 NM_144719
CCDC13
coiled-coil domain containing 13
chr17_-_26665220 1.072 NM_006495
EVI2B
ecotropic viral integration site 2B
chr11_+_5667392 1.068 TRIM22
tripartite motif containing 22
chr20_-_5539487 1.059 NM_019593
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr6_-_30289092 1.057 NM_003449
TRIM26
tripartite motif containing 26
chr17_+_44642587 1.056 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr6_+_29799095 1.047 NM_001098478
NM_001098479
NM_018950
HLA-F


major histocompatibility complex, class I, F


chr22_-_37480898 1.042 SUN2
Sad1 and UNC84 domain containing 2
chr12_-_623056 1.037


chr9_+_5440455 1.037 NM_014143
CD274
CD274 molecule
chr12_+_46799279 1.031 NM_000289
PFKM
phosphofructokinase, muscle
chr3_-_15814678 1.028 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr11_-_47502115 1.026 NM_001172639
CELF1
CUGBP, Elav-like family member 1
chr13_+_42034871 1.026 NM_033012
TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
chr4_-_87500201 1.022 MAPK10
mitogen-activated protein kinase 10
chr1_-_25164061 1.014 NM_001031680
RUNX3
runt-related transcription factor 3
chr3_-_145049853 1.013 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr2_-_191587127 1.008 STAT1
signal transducer and activator of transcription 1, 91kDa
chr2_-_162883062 1.005 NM_022168
IFIH1
interferon induced with helicase C domain 1
chr19_+_10057972 1.000 C19orf66
chromosome 19 open reading frame 66
chr4_+_147316284 0.999 NM_007080
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr6_-_74284522 0.979 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr1_+_67404756 0.972 NM_144701
IL23R
interleukin 23 receptor
chr11_-_64327197 0.964 NM_004579
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr14_-_22358752 0.948 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr12_-_51887318 0.939 ITGB7
integrin, beta 7
chr12_-_119038995 0.921 NM_001167606
NM_006861
RAB35

RAB35, member RAS oncogene family

chr13_+_107719977 0.911 NM_001145645
NM_006573
TNFSF13B

tumor necrosis factor (ligand) superfamily, member 13b

chr4_-_116254381 0.904 NM_022569
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr15_-_27349233 0.890 NDNL2
necdin-like 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.21 3.55e-09 GO:0006955 immune response
1.86 3.58e-08 GO:0002376 immune system process
5.49 4.19e-07 GO:0034340 response to type I interferon
5.30 2.35e-06 GO:0060337 type I interferon-mediated signaling pathway
5.30 2.35e-06 GO:0071357 cellular response to type I interferon
3.19 3.38e-06 GO:0019221 cytokine-mediated signaling pathway
2.40 3.63e-05 GO:0045087 innate immune response
2.88 5.17e-05 GO:0071345 cellular response to cytokine stimulus
2.18 2.38e-04 GO:0050776 regulation of immune response
1.77 5.64e-04 GO:0051704 multi-organism process
2.38 9.52e-04 GO:0034097 response to cytokine stimulus
1.86 1.33e-03 GO:0002682 regulation of immune system process
2.14 1.64e-03 GO:0051707 response to other organism
1.77 1.98e-03 GO:0006952 defense response
2.71 2.06e-03 GO:0046649 lymphocyte activation
2.48 2.95e-03 GO:0045321 leukocyte activation
1.38 1.02e-02 GO:0006950 response to stress
1.90 1.83e-02 GO:0009607 response to biotic stimulus
2.69 1.94e-02 GO:0009615 response to virus

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 2.68e-03 GO:0005515 protein binding